Pierre Marie
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Pierre Marie (9 September 1853 – 13 April 1940) was a French
neurologist Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal c ...
and political journalist close to the
SFIO The French Section of the Workers' International (french: Section française de l'Internationale ouvrière, SFIO) was a political party in France that was founded in 1905 and succeeded in 1969 by the modern-day Socialist Party. The SFIO was found ...
.


Medical Career

After finishing medical school, he served as an interne (1878), working as an assistant to neurologist
Jean-Martin Charcot Jean-Martin Charcot (; 29 November 1825 – 16 August 1893) was a French neurology, neurologist and professor of anatomical pathology. He worked on hypnosis and hysteria, in particular with his hysteria patient Louise Augustine Gleizes. Charcot ...
(1825–1893) at the Salpêtrière and Bicêtre Hospitals in Paris. In 1883 he received his medical doctorate with a graduate thesis on
Basedow’s disease Graves' disease (german: Morbus Basedow), also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid. It frequently results in and is the most common cause of hyperthyroidism. It also often results in an enlarged thyr ...
, being promoted to ''médecin des hôpitaux'' several years later (1888). In 1907 he attained the chair of
pathological anatomy Anatomical pathology (''Commonwealth'') or Anatomic pathology (''U.S.'') is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination ...
at the Faculty of Medicine, and in 1917 was appointed to the chair of
neurology Neurology (from el, wikt:νεῦρον, νεῦρον (neûron), "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine), medicine dealing with the diagnosis and treatment of all categories of co ...
, a position he held until 1925. In 1911 Marie became a member of the ''
Académie de Médecine An academy ( Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy ...
''. One of Marie's earlier contributions was a description of a disorder of the
pituitary gland In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland, about the size of a chickpea and weighing, on average, in humans. It is a protrusion off the bottom of the hypothalamus at the base of the brain. The ...
known as
acromegaly Acromegaly is a disorder that results from excess growth hormone (GH) after the growth plates have closed. The initial symptom is typically enlargement of the hands and feet. There may also be an enlargement of the forehead, jaw, and nose. Other ...
. His analysis of the disease was an important contribution in the emerging field of
endocrinology Endocrinology (from '' endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental event ...
. Marie is also credited as the first to describe pulmonary hypertrophic osteoarthropathy,
cleidocranial dysostosis Cleidocranial dysostosis (CCD), also called cleidocranial dysplasia, is a birth defect that mostly affects the bones and teeth. The collarbones are typically either poorly developed or absent, which allows the shoulders to be brought close togethe ...
and
rhizomelic Rhizomelia refers to either a disproportion of the length of the proximal limb, such as the shortened limbs of achondroplasia, or some other disorder of the hip or shoulder. According to Stedman's medical dictionary "rhizomelic" means "relating to ...
spondylosis Spondylosis is the degeneration of the vertebral column from any cause. In the more narrow sense it refers to spinal osteoarthritis, the age-related wear and tear of the spinal column, which is the most common cause of spondylosis. The degenera ...
. In his extensive research of
aphasia Aphasia is an inability to comprehend or formulate language because of damage to specific brain regions. The major causes are stroke and head trauma; prevalence is hard to determine but aphasia due to stroke is estimated to be 0.1–0.4% in th ...
, his views concerning language disorders sharply contrasted the generally accepted views of
Paul Broca Pierre Paul Broca (, also , , ; 28 June 1824 – 9 July 1880) was a French physician, anatomist and anthropologist. He is best known for his research on Broca's area, a region of the frontal lobe that is named after him. Broca's area is involve ...
(1824–1880). In 1907, he was the first person to describe the
speech production Speech production is the process by which thoughts are translated into speech. This includes the selection of words, the organization of relevant grammatical forms, and then the articulation of the resulting sounds by the motor system using the vo ...
disorder of
foreign accent syndrome Foreign accent syndrome is a medical condition in which patients develop speech patterns that are perceived as a foreign accent that is different from their native accent, without having acquired it in the perceived accent's place of origin. Fo ...
. Marie was the first general secretary of the ''Société Française de Neurologie'', and with
Édouard Brissaud Édouard Brissaud (15 April 1852, Besançon – 20 December 1909) was a French physician and pathologist. He was taught by Jean Martin Charcot at Pitié-Salpêtrière Hospital. He had interests in a number of medical disciplines including motion di ...
(1852–1909), he was co-founder of the journal ''Revue neurologique''. His name is associated with the eponymous
Charcot–Marie–Tooth disease Charcot–Marie–Tooth disease (CMT) is a hereditary motor and sensory neuropathy of the peripheral nervous system characterized by progressive loss of muscle tissue and touch sensation across various parts of the body. This disease is the mos ...
, being named along with
Jean-Martin Charcot Jean-Martin Charcot (; 29 November 1825 – 16 August 1893) was a French neurology, neurologist and professor of anatomical pathology. He worked on hypnosis and hysteria, in particular with his hysteria patient Louise Augustine Gleizes. Charcot ...
and
Howard Henry Tooth Howard Henry Tooth (1856–1925) was a British neurologist and one of the discoverers of Charcot–Marie–Tooth disease. Early life and education Dr. Tooth was born on 22 April 1856 to Frederick Tooth of Hove, Sussex, England. He attended Ru ...
(1856–1925). This disease is characterized by gradual progressive loss of distal muscle tissue in the arms and feet. It is considered the most common disease within a group of conditions known as "hereditary motor and sensory neuropathies" (HMSN). Among the doctors trained by Pierre Marie at the beginning of the 20th century account the Spanish neuropathologists Nicolás Achúcarro and
Gonzalo Rodríguez Lafora Gonzalo Rodríguez Lafora (25 July 1886 – 27 December 1971) was a Spanish neurologist. He was a disciple of Nicolás Achúcarro and Santiago Ramón y Cajal and one of the most brilliant examples of the Spanish Neurological School (or Cajal Scho ...
, two distinguished disciples of
Santiago Ramón y Cajal Santiago Ramón y Cajal (; 1 May 1852 – 17 October 1934) was a Spanish neuroscientist, pathologist, and histologist specializing in neuroanatomy and the central nervous system. He and Camillo Golgi received the Nobel Prize in Physiology or Med ...
and members of the
Spanish Neurological School Spanish might refer to: * Items from or related to Spain: **Spaniards are a nation and ethnic group indigenous to Spain **Spanish language, spoken in Spain and many Latin American countries **Spanish cuisine Other places * Spanish, Ontario, Cana ...
.


Political career

From 1928, Marie left the medical academy to become a political journalist, first at physical-culturist magazine La Culture Physique, where
Edmond Desbonnet Edmond Desbonnet (1867–1953) was a French academic and photographer who championed physical culture. He made physical education fashion Fashion is a form of self-expression and autonomy at a particular period and place and in a specific co ...
served as his intellectual patron. His writings largely centred around his recommendations of exercise and fitness regimes, and his commentary on government sports and leisure policy. In 1930, he turned to explicitly political writing as he moved to the Socialist Party's daily newspaper,
Le Populaire ''Le Populaire'' is a major independent daily newspaper in Senegal Senegal,; Wolof: ''Senegaal''; Pulaar: 𞤅𞤫𞤲𞤫𞤺𞤢𞥄𞤤𞤭 (Senegaali); Arabic: السنغال ''As-Sinighal'') officially the Republic of Senegal,; Wolof: ...
. He became increasingly involved in the
SFIO The French Section of the Workers' International (french: Section française de l'Internationale ouvrière, SFIO) was a political party in France that was founded in 1905 and succeeded in 1969 by the modern-day Socialist Party. The SFIO was found ...
in the 1930s, gaining a reputation as the Party's foremost intellectual on matters of sports, leisure, and physical culture. His 1934 pamphlet, "Pour Le Sport Ouvrier", was adopted by the SFIO's Congress as official Party policy. This marked the first time the SFIO embraced physical culture explicitly. After the election of the French Popular Front in 1936, he worked in the ministerial cabinet of
Léo Lagrange Léo Lagrange (; 28 November 1900, in Bourg, Gironde, Bourg – 9 June 1940, in Évergnicourt) was a French Socialist, member of the SFIO, named secretary of State in the Popular Front government of Léon Blum. Biography As a child, Lagran ...
as a technical advisor, where he became a noted advocate of working-class sports and social hygiene within the French government. He is a rare figure to bridge the gap between French physical culturism and Socialism. After the fall of the Popular Front, Marie continued to write for Le Populaire. Historians have disagreed about the date of Marie's death. While most medical sources place his death before Occupation, noted historian
Pascal Ory Pascal Ory (born 31 July 1948) is a French historian. A student of René Rémond, he specialises in cultural and political history and has written on Fascism ever since his master's dissertation on the Greenshirts of Henri Dorgères. In the 1 ...
recently uncovered traces of Marie's writing in collaborationist newspapers Le Rouge et Le Bleu in support of the
Vichy regime Vichy France (french: Régime de Vichy; 10 July 1940 – 9 August 1944), officially the French State ('), was the fascist French state headed by Marshal Philippe Pétain during World War II. Officially independent, but with half of its terr ...
until 1941. His collaborationism has led some historians to understand the influence of physical culture in the SFIO and the Vichy Regime as one path that led many Socialists - like Marie - to supporting Pétain.


Associated eponyms

* "Marie's ataxia": an hereditary disease of the
nervous system In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body. The nervous system detects environmental changes th ...
, with
cerebellar ataxia Cerebellar ataxia is a form of ataxia originating in the cerebellum. Non-progressive congenital ataxia (NPCA) is a classical presentation of cerebral ataxias. Cerebellar ataxia can occur as a result of many diseases and may present with symptoms ...
. * "Marie-Foix-Alajouanine syndrome":
cerebellar ataxia Cerebellar ataxia is a form of ataxia originating in the cerebellum. Non-progressive congenital ataxia (NPCA) is a classical presentation of cerebral ataxias. Cerebellar ataxia can occur as a result of many diseases and may present with symptoms ...
of the
cerebellum The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as or even larger. In humans, the cerebel ...
in the elderly; usually due to alcohol abuse. Named along with neurologists Théophile Alajouanine (1890–1980) and
Charles Foix Charles Foix (; 1 February 1882 – 22 March 1927) was a French internist and neurologist. Charles Foix was born in Salies-de-Béarn, Pyrénées-Atlantiques. He studied medicine at the University of Paris and was a pupil of Pierre Marie at the Pit ...
(1882–1927). * "Marie's anarthria": inability to articulate words due to cerebral lesions. * "Marie–Strümpel Disease": also known as
ankylosing spondylitis Ankylosing spondylitis (AS) is a type of arthritis characterized by long-term inflammation of the joints of the spine typically where the spine joins the pelvis. Occasionally areas affected may include other joints such as the shoulders or hip ...
; a severe arthritic spinal deformity. Named along with German neurologist Adolph Strümpell (1853–1925). The disease is sometimes referred to as "Bekhterev Disease"; named after Russian neurophysiologist
Vladimir Bekhterev Vladimir Mikhailovich Bekhterev ( rus, Влади́мир Миха́йлович Бе́хтерев, p=ˈbʲextʲɪrʲɪf; January 20, 1857 – December 24, 1927) was a Russian neurologist and the father of objective psychology. He is best know ...
(1857–1927). * "Marie-Léri syndrome": hand deformity caused by
osteolysis Osteolysis is an active resorption of bone matrix by osteoclasts and can be interpreted as the reverse of ossification. Although osteoclasts are active during the natural formation of healthy bone the term "osteolysis" specifically refers to a path ...
of the articular surfaces of the fingers. Named with neurologist
André Léri André Léri (1875 - 8 September 1930) was a French neurologist born in Paris. He studied medicine in Paris, where he was a student of Joseph Babinski (1857–1932) and Pierre Marie (1853–1940). In 1904 he obtained his doctorate with a disserta ...
(1875–1930). * "Bamberger-Marie disease": also known as
hypertrophic pulmonary osteoarthropathy Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. Distal expansion of the long bones as well as painf ...
. Named with Austrian internist
Eugen von Bamberger Eugen von Bamberger (5 September 1858 – October 1921) was an Austrian internist born in Würzburg, Germany. He was the son of pathologist Heinrich von Bamberger (1822–1888). He studied medicine at the Universities of Vienna and Würzburg, rece ...
(1858–1921).


Selected writings

Medical Writings: *''Des formes frustes de la maladie de Basedow'', doctoral thesis, Paris, 1883. * ''Sur deux cas d’acromégalie'', 1886. * ''Sur une form particulière d'atrophie musculaire progressive; souvent familiale, débutant par les pieds et les jambes et atteignant tard les mains'', With Jean Martin Charcot. 1886 * "Essays on
Acromegaly Acromegaly is a disorder that results from excess growth hormone (GH) after the growth plates have closed. The initial symptom is typically enlargement of the hands and feet. There may also be an enlargement of the forehead, jaw, and nose. Other ...
", with bibliography and appendix of cases by other authors.
London London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a majo ...
, 1891. * ''Leçons sur les maladies de la moëlle épinière'', Paris, 1892. English translation by M. Lubbock as "Lectures on Diseases of the Spinal Cord", London, 1895. * ''Sur l'hérédo-ataxie cérébelleuse'', Semaine médicale, Paris, 1893, 13: 444. * ''L’évolution du langage considéré au point de vue de l’étude de l’Aphasie'', 1897. * ''Dysostose cléido-crânienne héréditaire'', with Paul Sainton (1868–1958); 1897. * ''Spondylose rhizomélique'', 1898. * ''Neurologie'', two volumes; 1923. Political Writings: * ''Force et Santé Pour Tous, ou Le Triomphe de La Culture Physique'' (1928) * ''Pour La Santé du Sédentaire'' (1931) * ''Pour Le Sport Ouvrier'' (1934)


See also

*
A Clinical Lesson at the Salpêtrière ''A Clinical Lesson at the Salpêtrière'' (french: Une leçon clinique à la Salpêtrière) is an 1887 group tableau portrait painted by the history and genre artist André Brouillet (1857–1914). The painting, one of the best-known in the hi ...


References


Bibliography


''Pierre Marie''
@
Who Named It ''Whonamedit?'' is an online English-language dictionary of medical eponyms and the people associated with their identification. Though it is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliograph ...
(biography) * {{DEFAULTSORT:Marie, Pierre French neurologists 1853 births 1940 deaths Physicians from Paris French endocrinologists Ankylosing spondylitis Journalists from Paris